Epr plays a key role in DegU-mediated swarming motility ofBacillus subtilis
نویسندگان
چکیده
منابع مشابه
Extracellular proteolytic activity plays a central role in swarming motility in Bacillus subtilis.
Natural isolates of Bacillus subtilis exhibit a robust multicellular behavior known as swarming. A form of motility, swarming is characterized by a rapid, coordinated progression of a bacterial population across a surface. As a collective bacterial process, swarming is often associated with biofilm formation and has been linked to virulence factor expression in pathogenic bacteria. While the sw...
متن کاملLaboratory strains of Bacillus subtilis do not exhibit swarming motility.
We redemonstrate that SwrA is essential for swarming motility in Bacillus subtilis, and we reassert that laboratory strains of B. subtilis do not swarm. Additionally, we find that a number of other genes, previously reported to be required for swarming in laboratory strains, are dispensable for robust swarming motility in an undomesticated strain. We attribute discrepancies in the literature to...
متن کاملepr Is Transcribed from a D Promoter and Is Involved in Swarming of Bacillus subtilis
At the onset of stationary phase, Bacillus subtilis secretes at least seven extracellular proteases of which subtilisin (aprE) and a neutral metalloprotease E (nprE) are the most abundant (6). Of the remaining five minor extracellular proteases, Epr (epr) contributes 2 to 4% to this pool (18). The expression of these enzymes is stringently regulated, as best exemplified by the aprE gene (23). H...
متن کاملInnate Immunity Plays a Key Role in Leishmania Infection: Implications for Vaccine Design
Neutrophils are part of the first line of immune response and are essential for resistance against a variety of pathogens. They professionally mediate direct killing of pathogens, recruit other phagocytes by specific chemokines, produce cytokines and interact with different immune cells to shape the adaptive response. Leishmania as an obligatory intracellular parasite has evolved to benefit thi...
متن کاملDegU-P represses expression of the motility fla-che operon in Bacillus subtilis.
Bacillus subtilis implements several adaptive strategies to cope with nutrient limitation experienced at the end of exponential growth. The DegS-DegU two-component system is part of the network involved in the regulation of postexponential responses, such as competence development, the production of exoenzymes, and motility. The degU32(Hy) mutation extends the half-life of the phosphorylated fo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 2009
ISSN: 0378-1097,1574-6968
DOI: 10.1111/j.1574-6968.2009.01596.x